There is no question that the projected growth of meat production is intimately associated with many ecological issues. It is safe to predict that meat sustainability and ecology are on a collision course. The huge requirements of fresh water, particularly for meat-producing animals, could eventually have a catastrophic impact on the environment. The world needs to make hard choices and will, at some point, be forced to accept a diet with less traditionally harvested animal protein, and instead move to precision fermentation technologies in which gene expression is used to produce cultured meat and milk proteins, as well as embrace molecular agriculture for food security.